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CPD Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75976 |
| Other Accession | Q9JHW1, O89001 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 152931 Da |
| Antigen Region | 1019-1048 aa |
| Gene ID | 1362 |
|---|---|
| Other Names | Carboxypeptidase D, Metallocarboxypeptidase D, gp180, CPD |
| Target/Specificity | This CPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1019-1048 amino acids from the C-terminal region of human CPD. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CPD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CPD |
|---|---|
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q90240}; Single-pass type I membrane protein |
| Tissue Location | Highly expressed in placenta, pancreas and hepatoma cells. Lower levels found in skeletal muscle, heart and colon carcinoma and melanoma cell lines |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein.
References
Hoff,N.P., J. Clin. Immunol. 27 (6), 568-579 (2007)
O'Malley,P.G., Biochem. J. 390 (PT 3), 665-673 (2005)
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