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CHC1L Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | O95199 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 60315 Da |
| Antigen Region | 71-99 aa |
| Gene ID | 1102 |
|---|---|
| Other Names | RCC1 and BTB domain-containing protein 2, Chromosome condensation 1-like, CHC1-L, RCC1-like G exchanging factor, Regulator of chromosome condensation and BTB domain-containing protein 2, RCBTB2, CHC1L, RLG |
| Target/Specificity | This CHC1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human CHC1L. |
| Dilution | WB~~1:2000 FC~~1:10~50 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHC1L Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RCBTB2 |
|---|---|
| Synonyms | CHC1L, RLG |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q99LJ7}. Note=Mainly found in the acrosomal cap region. {ECO:0000250|UniProtKB:Q99LJ7} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RCBTB2 is a member of the RCC1-related GEF family. The N-terminal half of the amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.
References
Latil,A., Int. J. Cancer 99 (5), 689-696 (2002)
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