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ABHD11 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8NFV4 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33747 Da |
| Gene ID | 83451 |
|---|---|
| Other Names | ABHD11; WBSCR21; PP1226; Abhydrolase domain-containing protein 11; Williams-Beuren syndrome chromosomal region 21 protein |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | ABHD11 (HGNC:16407) |
|---|---|
| Synonyms | WBSCR21 |
| Function | Catalyzes the hydrolysis of diacylglycerol in vitro and may function as a key regulator in lipid metabolism, namely by regulating the intracellular levels of diacylglycerol (PubMed:32579589). 1,2- diacyl-sn-glycerols are the preferred substrate over 1,3-diacyl-sn- glycerols (By similarity). The enzyme hydrolyzes stearate in preference to palmitate from the sn-1 position of 1,2-diacyl-sn-glycerols (By similarity). Maintains the functional lipoylation of the 2-oxoglutarate dehydrogenase complex (OGDHc) through its interaction with the OGDHc by preventing the formation of lipoyl adducts (PubMed:32792488). In addition, is also required for the expansion and differentiation of embryonic stem cells (ESCs) (By similarity). |
| Cellular Location | Mitochondrion. Mitochondrion matrix |
| Tissue Location | Ubiquitously expressed (PubMed:12073013). Highly expressed in small intestine, prostate and thyroid, while aorta and colon tissues exhibit weak expression levels (PubMed:32579589) |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP68237
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