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Cdc42EP2 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O14613 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 22484 Da |
| Gene ID | 10435 |
|---|---|
| Other Names | CDC42EP2; BORG1; CEP2; Cdc42 effector protein 2; Binder of Rho GTPases 1 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | CDC42EP2 |
|---|---|
| Synonyms | BORG1, CEP2 |
| Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. |
| Cellular Location | Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton |
| Tissue Location | Highly expressed in the heart. Weakly expressed in the pancreas and liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner.
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