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KDEL Receptor 3 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O43731 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25027 Da |
| Gene ID | 11015 |
|---|---|
| Other Names | KDELR3; ER lumen protein retaining receptor 3; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor 3 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | KDELR3 |
|---|---|
| Synonyms | ERD23 {ECO:0000303|PubMed:18086916} |
| Function | Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. |
| Cellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Golgi apparatus membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Cytoplasmic vesicle, COPI-coated vesicle membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q5ZKX9}. Note=Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L |
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for the retention of luminal endoplasmic reticulum proteins. Determines the specificity of the luminal ER protein retention system. Also required for normal vesicular traffic through the Golgi. This receptor recognizes K-D-E-L (By similarity).
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