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LASS4 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9HA82 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46399 Da |
| Gene ID | 79603 |
|---|---|
| Other Names | CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4 |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | CERS4 {ECO:0000303|PubMed:17977534, ECO:0000312|HGNC:HGNC:23747} |
|---|---|
| Function | Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D6J1}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).
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