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HGFA Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q04756 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 70682 Da |
| Gene ID | 3083 |
|---|---|
| Other Names | HGFAC; Hepatocyte growth factor activator; HGF activator; HGFA |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | HGFAC (HGNC:4894) |
|---|---|
| Function | Serine protease that hydrolyzes the inactive zymogen hepatocyte growth factor (HGFsc) to an activated disulfide-linked heterodimer, then initiating hepatocyte growth factor receptor signaling pathway. |
| Cellular Location | Secreted. Note=Exists as an inactive zymogen in plasma (PubMed:8226803). Exists as an active heterodimeric form in serum (PubMed:7683665). |
| Tissue Location | Liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
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