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Sg III Polyclonal Antibody
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- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q8WXD2 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 53005 Da |
| Gene ID | 29106 |
|---|---|
| Other Names | SCG3; Secretogranin-3; Secretogranin III; SgIII |
| Dilution | WB~~Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | SCG3 |
|---|---|
| Function | Member of the granin protein family that regulates the biogenesis of secretory granules (PubMed:19357184). Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA (By similarity). May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed:29154827). |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle {ECO:0000250|UniProtKB:P47868}. Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:P47868}; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to cholesterol-enriched lipid rafts. {ECO:0000250|UniProtKB:P47868} |
| Tissue Location | Detected in urine (at protein level) (PubMed:25326458). Expressed in brain, heart, kidney, liver and skeletal muscle. |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP73325
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