CDNF Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
 
| Application  
 | IHC-P | 
|---|---|
| Primary Accession | Q49AH0 | 
| Reactivity | Human | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Calculated MW | 20964 Da | 
| Gene ID | 441549 | 
|---|---|
| Other Names | Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor) | 
| Dilution | IHC-P~~N/A | 
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. | 
| Storage Conditions | -20℃ | 
| Name | CDNF | 
|---|---|
| Synonyms | ARMETL1 | 
| Function | Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | 
| Cellular Location | Secreted | 
| Tissue Location | Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum. | 

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Provided below are standard protocols that you may find useful for product applications.
Background
Trophic factor for dopamine neurons. Prevents the 6- hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).

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