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ASPP1 Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | Q96KQ4 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 119565 Da |
| Gene ID | 23368 |
|---|---|
| Other Names | Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B) |
| Dilution | IHC-P~~N/A |
| Format | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide. |
| Storage Conditions | -20℃ |
| Name | PPP1R13B |
|---|---|
| Synonyms | ASPP1, KIAA0771 |
| Function | Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (PubMed:11684014, PubMed:12524540). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. |
| Cellular Location | Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Some fraction is nuclear |
| Tissue Location | Reduced expression in breast carcinomas expressing a wild-type TP53 protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
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