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ALAS2 Rabbit mAb

     
  • WB - ALAS2 Rabbit mAb AP75047
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession P22557
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 64633 Da
Additional Information
Gene ID 212
Other Names ALAS2
Dilution WB~~1/500-1/1000
IP~~N/A
Format Liquid
Protein Information
Name ALAS2 {ECO:0000303|PubMed:34492704, ECO:0000312|HGNC:HGNC:397}
Function Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products (PubMed:14643893, PubMed:21252495, PubMed:21309041, PubMed:21653323, PubMed:32499479, PubMed:34492704). Contributes significantly to heme formation during erythropoiesis (PubMed:2050125).
Cellular Location Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Tissue Location [Isoform 1]: Erythroid-specific. [Isoform 3]: Erythroid-specific.
Research Areas
Citations (0)
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$ 385.00
Cat# AP75047
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