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MGST3 Rabbit mAb

     
  • WB - MGST3 Rabbit mAb AP75717
    detail
  • IHC - MGST3 Rabbit mAb AP75717
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession O14880
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 16516 Da
Additional Information
Gene ID 4259
Other Names MGST3
Dilution WB~~1/500-1/1000
IHC-P~~N/A
IP~~N/A
Format Liquid
Protein Information
Name MGST3 (HGNC:7064)
Function Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids, as part of cellular detoxification as well as synthesis of bioactive metabolites (PubMed:36370807, PubMed:9278457). Catalyzes conjugate addition of reduced glutathione to the alpha, beta-unsaturated C=C carbonyl group of eisosanoids such as leukotriene A4 and 15-deoxy-Delta12,14- prostaglandin J2 to form GSH adducts relevant to the inflammatory response (PubMed:36370807, PubMed:9278457). Catalyzes glutathione- dependent reduction of eicosanoid peroxides to yield the corresponding eicosanoid hydroxides (PubMed:9278457).
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein
Tissue Location Predominantly expressed in heart, skeletal muscle, and adrenal cortex. Also found in brain, placenta, liver, kidney, pancreas, thyroid, testis and ovary. Almost absent in lung, thymus and peripheral blood leukocytes. Expressed in mast cells
Research Areas
Citations (0)
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$ 385.00
Cat# AP75717
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