MST4 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP, ICC |
---|---|
Primary Accession | Q9P289 |
Reactivity | Human, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 46529 Da |
Gene ID | 51765 |
---|---|
Other Names | STK26 |
Dilution | WB~~1/500-1/1000 IP~~N/A ICC~~N/A |
Format | Liquid |
Name | STK26 (HGNC:18174) |
---|---|
Function | Serine/threonine-protein kinase that acts as a mediator of cell growth (PubMed:11641781, PubMed:17360971). Modulates apoptosis (PubMed:11641781, PubMed:17360971). In association with STK24 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Phosphorylates ATG4B at 'Ser- 383', thereby increasing autophagic flux (PubMed:29232556). Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (PubMed:18782753). |
Cellular Location | Cytoplasm. Golgi apparatus Note=Colocalized with RIPOR1 in the Golgi of serum-starved cells and relocated to cytoplasmic punctae, probably vesicular compartments, along with RIPOR1 upon serum stimulation in a Rho- and PDCD10-dependent manner (PubMed:27807006). |

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