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NIT1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | Q86X76 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 35896 Da |
| Gene ID | 4817 |
|---|---|
| Other Names | NIT1 |
| Dilution | WB~~1/500-1/1000 IP~~N/A |
| Format | Liquid |
| Name | NIT1 |
|---|---|
| Function | Catalyzes the hydrolysis of the amide bond in N-(4- oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. |
| Cellular Location | [Isoform 2]: Mitochondrion {ECO:0000250|UniProtKB:Q8VDK1} |
| Tissue Location | Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP75811
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