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PCGF6 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, ICC |
|---|---|
| Primary Accession | Q99NA9 |
| Reactivity | Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 39820 Da |
| Gene ID | 71041 |
|---|---|
| Other Names | Pcgf6 |
| Dilution | WB~~1/500-1/1000 IP~~N/A ICC~~N/A |
| Format | Liquid |
| Name | Pcgf6 |
|---|---|
| Synonyms | Mblr, Rnf134 |
| Function | Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9BYE7}. |
| Tissue Location | Expressed in ovary, testis, stomach, liver, thymus and kidney (at protein level). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP75875
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