RAMP1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | O60894 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 16988 Da |
Gene ID | 10267 |
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Other Names | RAMP1 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | RAMP1 (HGNC:9843) |
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Function | Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene- related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR) (PubMed:33602864, PubMed:9620797, PubMed:35324283, PubMed:38603770). Required for the transport of CALCRL to the plasma membrane (PubMed:9620797). Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB (PubMed:33602864, PubMed:9620797). Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA (PubMed:35324283, PubMed:38603770). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract |

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