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RAP1 Rabbit mAb
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- CITATIONS
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- BACKGROUND
Application 
| WB, IP |
|---|---|
| Primary Accession | P61224 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 20825 Da |
| Gene ID | 5908 |
|---|---|
| Other Names | RAP1B |
| Dilution | WB~~1/500-1/1000 IP~~N/A |
| Format | Liquid |
| Name | RAP1B |
|---|---|
| Function | GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. |
| Cellular Location | Cell membrane. Cytoplasm, cytosol. Cell junction. Note=May shuttle between plasma membrane and cytosol (PubMed:3141412). Presence of KRIT1 and CDH5 is required for its localization to the cell junction (PubMed:20332120) |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP76002
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