IKZF3 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P |
|---|---|
| Primary Accession | Q9UKT9 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Monoclonal Antibody |
| Calculated MW | 58023 Da |
| Gene ID | 22806 |
|---|---|
| Other Names | IKZF3 |
| Dilution | WB~~1/500-1/1000 IHC-P~~N/A |
| Format | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Name | IKZF3 |
|---|---|
| Synonyms | ZNFN1A3 |
| Function | Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner. |
| Cellular Location | Nucleus. Cytoplasm [Isoform 3]: Nucleus [Isoform 14]: Nucleus. Cytoplasm |
| Tissue Location | Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. |

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