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MYH10 Rabbit mAb

     
  • WB - MYH10 Rabbit mAb AP76622
    detail
  • IP - MYH10 Rabbit mAb AP76622
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession P35580
Reactivity Human, Mouse
Host Rabbit
Clonality Monoclonal Antibody
Calculated MW 228999 Da
Additional Information
Gene ID 4628
Other Names MYH10
Dilution WB~~1/500-1/1000
IP~~1/20
Format Liquid
Protein Information
Name MYH10
Function Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9.
Cellular Location Cell projection, lamellipodium Note=Colocalizes with MCC at the leading edge of migrating cells
Tissue Location Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum
Research Areas
Citations (0)
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$ 385.00
Cat# AP76622
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