MYH10 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP |
---|---|
Primary Accession | P35580 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 228999 Da |
Gene ID | 4628 |
---|---|
Other Names | MYH10 |
Dilution | WB~~1/500-1/1000 IP~~1/20 |
Format | Liquid |
Name | MYH10 |
---|---|
Function | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the central part but not the margins of spreading cells), and lamellipodial extension; this function is mechanically antagonized by MYH9. |
Cellular Location | Cell projection, lamellipodium Note=Colocalizes with MCC at the leading edge of migrating cells |
Tissue Location | Isoform 1 is expressed in cerebellum and spinal chord. Isoform 2 is expressed in cerebrum and retina. Isoform 3 is expressed in the cerebrum and to a much lower extent in cerebellum |

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