Cathepsin B Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, ICC |
---|---|
Primary Accession | P10605 |
Reactivity | Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 37280 Da |
Gene ID | 13030 |
---|---|
Other Names | Ctsb |
Dilution | WB~~1/500-1/1000 ICC~~N/A |
Format | Liquid |
Name | Ctsb |
---|---|
Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (PubMed:12782676). Has also been implicated in tumor invasion and metastasis (By similarity). |
Cellular Location | Lysosome. Melanosome {ECO:0000250|UniProtKB:P07858}. Secreted, extracellular space. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells |
Tissue Location | Expressed in thyroid epithelial cells. |

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