IRF2 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, ICC |
---|---|
Primary Accession | P14316 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Calculated MW | 39354 Da |
Gene ID | 3660 |
---|---|
Other Names | IRF2 |
Dilution | WB~~1/500-1/1000 |
Format | Liquid |
Name | IRF2 |
---|---|
Function | Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. |
Cellular Location | Nucleus. |
Tissue Location | Expressed throughout the epithelium of the colon. Also expressed in lamina propria. |

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