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PR48 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9Y5P8 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65061 Da |
| Antigen Region | 25-54 aa |
| Gene ID | 28227 |
|---|---|
| Other Names | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta, PP2A subunit B isoform PR48, Protein phosphatase 2A 48 kDa regulatory subunit, PPP2R3B, PPP2R3L |
| Target/Specificity | This PR48 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human PR48. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PR48 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPP2R3B |
|---|---|
| Synonyms | PPP2R3L |
| Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. This protein belongs to the B'' family. The B'' family has been further divided into subfamilies. This protein belongs to the beta subfamily of regulatory subunit B''.
References
Stevens,I., Eur. J. Biochem. 270 (2), 376-387 (2003)
Yokoyama,N., Oncogene 20 (42), 6057-6065 (2001)
Yan,Z., Mol. Cell. Biol. 20 (3), 1021-1029 (2000)
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