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RIPK4 (ANKRD3) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RIPK4 (ANKRD3) Antibody (C-term) AP7808b
    Western blot analysis of anti-ANKRD3-Q817 Pab (Cat. #AP7808b) in mouse kidney tissue lysate (35ug/lane). ANKRD3-Q817(arrow) was detected using the purified Pab.
    detail
  • WB - RIPK4 (ANKRD3) Antibody (C-term) AP7808b
    ANKRD3 Antibody (Q817) (Cat. #AP7808b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ANKRD3 antibody detected the ANKRD3 protein (arrow).
    detail
  • IHC-P - RIPK4 (ANKRD3) Antibody (C-term) AP7808b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P57078
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 91611 Da
Antigen Region 802-832 aa
Additional Information
Other Names Receptor-interacting serine/threonine-protein kinase 4, Ankyrin repeat domain-containing protein 3, PKC-delta-interacting protein kinase, RIPK4, ANKRD3, DIK
Target/Specificity This RIPK4 (ANKRD3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human RIPK4 (ANKRD3).
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRIPK4 (ANKRD3) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIPK4
Synonyms ANKRD3, DIK
Function Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation.
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein
Tissue Location Expressed in hair follicles and skin.
Research Areas
Citations ( 0 )

Background

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.

References

Hattori, M., et al., Nature 405(6784):311-319 (2000).

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$ 365.00
$ 140.00
Cat# AP7808b
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