RIPK4 (ANKRD3) Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | P57078 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 91611 Da |
Antigen Region | 802-832 aa |
Other Names | Receptor-interacting serine/threonine-protein kinase 4, Ankyrin repeat domain-containing protein 3, PKC-delta-interacting protein kinase, RIPK4, ANKRD3, DIK |
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Target/Specificity | This RIPK4 (ANKRD3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human RIPK4 (ANKRD3). |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | RIPK4 (ANKRD3) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RIPK4 |
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Synonyms | ANKRD3, DIK |
Function | Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation. |
Cellular Location | Cytoplasm. Membrane; Peripheral membrane protein |
Tissue Location | Expressed in hair follicles and skin. |
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
References
Hattori, M., et al., Nature 405(6784):311-319 (2000).
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