Syntaxin Binding Protein 1 Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC-P, IF, ICC |
---|---|
Primary Accession | P61764 |
Reactivity | Rat, Human, Mouse |
Host | Rabbit |
Clonality | Monoclonal Antibody |
Isotype | IgG |
Conjugate | Unconjugated |
Immunogen | A synthesized peptide derived from human STXBP1 |
Purification | Affinity Purified |
Calculated MW | Calculated MW: 68 kDa; Observed MW: 65 kDa |
Gene ID | 6812 |
---|---|
Other Names | STXBP1 |
Dilution | WB~~1/500-1/1000 IHC-P~~N/A IF~~1:50~200 ICC~~N/A |
Format | Liquid in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Name | STXBP1 |
---|---|
Synonyms | UNC18A |
Function | Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. Involved in the release of neurotransmitters from neurons through interacting with SNARE complex component STX1A and mediating the assembly of the SNARE complex at synaptic membranes (By similarity). May play a role in determining the specificity of intracellular fusion reactions. |
Cellular Location | Cytoplasm, cytosol. Membrane; Peripheral membrane protein |
Tissue Location | Brain and spinal cord. Highly enriched in axons. |

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