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UTS2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | O95399 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 14296 Da |
| Antigen Region | 10-39 aa |
| Gene ID | 10911 |
|---|---|
| Other Names | Urotensin-2, Urotensin II, U-II, UII, UTS2 |
| Target/Specificity | This UTS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human UTS2. |
| Dilution | FC~~1:10~50 IHC-P~~1:10~50 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UTS2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UTS2 |
|---|---|
| Function | Highly potent vasoconstrictor. |
| Cellular Location | Secreted. |
| Tissue Location | Brain specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
UTS2 is a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this protein is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
References
Brailoiu,E., Peptides 29 (5), 721-726 (2008)
Cirillo,P., J. Thromb. Haemost. 6 (5), 726-736 (2008)
Zoccali,C.Hypertension 51 (2), 326-333 (2008)
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