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AKAP3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O75969 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 94751 Da |
| Antigen Region | 240-267 aa |
| Gene ID | 10566 |
|---|---|
| Other Names | A-kinase anchor protein 3, AKAP-3, A-kinase anchor protein 110 kDa, AKAP 110, Cancer/testis antigen 82, CT82, Fibrous sheath protein of 95 kDa, FSP95, Fibrousheathin I, Fibrousheathin-1, Protein kinase A-anchoring protein 3, PRKA3, Sperm oocyte-binding protein, AKAP3, AKAP110, SOB1 |
| Target/Specificity | This AKAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-267 amino acids from the Central region of human AKAP3. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | AKAP3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AKAP3 |
|---|---|
| Synonyms | AKAP110, SOB1 |
| Function | Has a role in the maintenance of acrosome structure (PubMed:35228300). May function as a regulator of both spermatozoa motility and head-associated functions such as capacitation and the acrosome reaction. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment |
| Tissue Location | Testis specific; only expressed in spermatids. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
AKAP3 may function as a regulator of both motility-and head-associated functions such as capacitation and the acrosome reaction.
References
Lefevre,A.,et.al., Biochem. Biophys. Res. Commun. 259 (1), 60-66 (1999)
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