CCL3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 2
- PROTOCOLS
- BACKGROUND
 
| Application  
 | IHC-P, WB, E | 
|---|---|
| Primary Accession | P10147 | 
| Other Accession | P16619 | 
| Reactivity | Human, Mouse | 
| Host | Rabbit | 
| Clonality | Polyclonal | 
| Isotype | Rabbit IgG | 
| Calculated MW | 10085 Da | 
| Antigen Region | 59-87 aa | 
| Gene ID | 6348 | 
|---|---|
| Other Names | C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 4641, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3 | 
| Target/Specificity | This CCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the C-terminal region of human CCL3. | 
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. | 
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | 
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 
| Precautions | CCL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | 
| Name | CCL3 | 
|---|---|
| Synonyms | G0S19-1, MIP1A, SCYA3 | 
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose- dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). | 
| Cellular Location | Secreted. | 

Provided below are standard protocols that you may find useful for product applications.
Background
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.
References
Hirashima,M., et.al., DNA Seq. 3 (4), 203-212 (1992) Blum,S., et.al., DNA Cell Biol. 9 (8), 589-602 (1990)

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