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LMOD1 Antibody (Center N201)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | P29536 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 67030 Da |
| Antigen Region | 214-241 aa |
| Gene ID | 25802 |
|---|---|
| Other Names | Leiomodin-1, 64 kDa autoantigen 1D, 64 kDa autoantigen 1D3, 64 kDa autoantigen D1, Leiomodin, muscle form, Smooth muscle leiomodin, SM-Lmod, Thyroid-associated ophthalmopathy autoantigen, LMOD1 |
| Target/Specificity | This LMOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-241 amino acids from the Central region of human LMOD1. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LMOD1 Antibody (Center N201) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LMOD1 |
|---|---|
| Function | Required for proper contractility of visceral smooth muscle cells (PubMed:28292896). Mediates nucleation of actin filaments. |
| Cellular Location | Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A0A0G2K0D3}. Note=Colocalizes with actin filaments in sarcomeres. {ECO:0000250|UniProtKB:A0A0G2K0D3} |
| Tissue Location | Detected in lung vascular smooth muscle (at protein level) (PubMed:27144530). Detected in thyroid and extraocular smooth muscle, but not skeletal muscle (PubMed:2026759). Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine (PubMed:11318603). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks.
References
Zhang,Z.G., et.al., Clin. Immunol. Immunopathol. 80 (3 PT 1), 236-244 (1996)
Conley,C.A.et.al., Curr. Eye Res. 19 (4), 313-322 (1999)
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