|Application ||FC, IHC-P, WB, E|
|Calculated MW||59268 Da|
|Antigen Region||312-339 aa|
|Other Names||Dolichol kinase, Transmembrane protein 15, DOLK, KIAA1094, TMEM15|
|Target/Specificity||This DOLK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-339 amino acids from the Central region of human DOLK.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DOLK Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
DOLK is involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors (By similarity).
Shridas,P. et.al., J. Biol. Chem. 281 (42), 31696-31704 (2006)
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