- CITATIONS: 1
|Application ||IHC-P, WB, E|
|Calculated MW||35578 Da|
|Antigen Region||281-307 aa|
|Other Names||Low affinity immunoglobulin gamma Fc region receptor II-c, IgG Fc receptor II-c, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, CD32, FCGR2C, CD32, FCG2, IGFR2|
|Target/Specificity||This FCGR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the C-terminal region of human FCGR2C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FCGR2C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD32, FCG2, IGFR2|
|Function||Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.|
|Cellular Location||[Isoform IIC4]: Cytoplasm. [Isoform IIC2]: Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells|
Provided below are standard protocols that you may find useful for product applications.
FCGR2C is the receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. It is involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
Metes D., et.al., Blood 91:2369-2380(1998).
Stuart S.G.,et.al., EMBO J. 8:3657-3666(1989).
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