Ras Antibody
Rabbit mAb
- SPECIFICATION
 - CITATIONS
 - PROTOCOLS
 - BACKGROUND
 
Application 
  | WB, FC, IP | 
|---|---|
| Primary Accession | P01111 | 
| Reactivity | Rat | 
| Clonality | Monoclonal | 
| Other Names | GTPase HRas;GTPase KRas;GTPase NRas;H-Ras-1;HAMSV;HRAS;HRAS1;K-RAS;N-RAS;NRAS;p21ras;RASH1;RASK2;Transforming protein p21 | 
| Isotype | Rabbit IgG | 
| Host | Rabbit | 
| Calculated MW | 21229 Da | 
| Dilution | WB 1:10000~1:20000 IP 1:20 FC 1:50 | 
|---|---|
| Purification | Affinity-chromatography | 
| Immunogen | A synthesized peptide derived from human Ras | 
| Description | HRas a small GTPase protein of the Ras family. Alternates between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP). Mutations are implicated in a variety of human tumors. | 
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. | 
| Name | NRAS | 
|---|---|
| Synonyms | HRAS1 | 
| Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | 
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor Note=Shuttles between the plasma membrane and the Golgi apparatus | 

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