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C3 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P01024 |
| Clonality | Monoclonal |
| Other Names | AHUS5; ARMD9; ASP; Complement C3; Complement factor 3; CPAMD1; HEL S 62p; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 187148 Da |
| Dilution | WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:20 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human C3 |
| Description | Plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | C3 {ECO:0000303|PubMed:2579379, ECO:0000312|HGNC:HGNC:1318} |
|---|---|
| Function | Precursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. |
| Cellular Location | Secreted. [C3a anaphylatoxin]: Secreted |
| Tissue Location | Plasma.. |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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If you have any additional inquiries please email technical services at tech@abcepta.com.
$ 195.00
$ 385.00
Cat# AP91124
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