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Caspr Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | P78357 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 156267 Da |
| Dilution | WB 1:500~1:2000 IHC 1:50~1:200 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Caspr |
| Description | Contactin-associated protein 2 (Caspr2) is a type I transmembrane protein and member of the neurexin superfamily that mediates nervous system cell-cell interactions through the Neurexin IV-Caspr-Paranodin (NCP) complex. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | CNTNAP1 |
|---|---|
| Synonyms | CASPR, NRXN4 |
| Function | Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. |
| Cellular Location | Membrane; Single-pass type I membrane protein. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:O54991} |
| Tissue Location | Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
$ 175.00
Cat# AP91434
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