Calretinin Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, FC, ICC |
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Primary Accession | P22676 |
Reactivity | Rat |
Clonality | Monoclonal |
Other Names | 29 kDa calbindin; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; Calretinin; CR; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 31540 Da |
Dilution | WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Calretinin |
Description | Calretinin is a calcium-binding protein which is abundant in auditory neurons. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | CALB2 (HGNC:1435) |
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Synonyms | CAB29 |
Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways (PubMed:2001709). Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory (By similarity). During embryonic development, it facilitates neuronal differentiation and maturation (By similarity). |
Cellular Location | Synapse {ECO:0000250|UniProtKB:Q08331}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q08331}. Note=Located in dendrioles, small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell {ECO:0000250|UniProtKB:Q08331} |
Tissue Location | Brain. |

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