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DSTN Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | P60981 |
| Other Accession | Q7M0E3, P60982, Q9R0P5, Q5E9D5 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Pig, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 18506 Da |
| Antigen Region | 70-98 aa |
| Gene ID | 11034 |
|---|---|
| Other Names | Destrin, Actin-depolymerizing factor, ADF, DSTN, ACTDP, DSN |
| Target/Specificity | This DSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human DSTN. |
| Dilution | WB~~1:1000 FC~~1:10~50 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DSTN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DSTN |
|---|---|
| Synonyms | ACTDP, DSN |
| Function | Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner. |
| Tissue Location | Widely distributed in various tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This protein encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
References
Estornes,Y., et.al., Int. J. Cancer 121 (10), 2162-2171 (2007)
Mannherz,H.G., et.al., J. Mol. Biol. 366 (3), 745-755 (2007)
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