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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ELOVL2 Antibody (N-term)   

ELOVL2 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ELOVL2 Antibody (N-term) AP9191a
    Western blot analysis of ELOVL2 Antibody (N-term) (Cat. #AP9191a) in HepG2 cell line lysates (35ug/lane). ELOVL2 (arrow) was detected using the purified Pab.
  • IHC-P - ELOVL2 Antibody (N-term) AP9191a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with ELOVL2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - ELOVL2 Antibody (N-term) AP9191a
    ELOVL2 Antibody (N-term) (Cat. #AP9191a) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NXB9
Other Accession Q9JLJ4
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34585 Da
Antigen Region 1-27 aa
Additional Information
Gene ID 54898
Other Names Elongation of very long chain fatty acids protein 2, 3-keto acyl-CoA synthase ELOVL2, ELOVL fatty acid elongase 2, ELOVL FA elongase 2, Very-long-chain 3-oxoacyl-CoA synthase 2, ELOVL2, SSC2
Target/Specificity This ELOVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human ELOVL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsELOVL2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELOVL2 {ECO:0000255|HAMAP-Rule:MF_03202}
Function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA), acting specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. May participate in the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Cellular Location Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03202, ECO:0000269|PubMed:20937905}; Multi- pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03202}
Tissue Location Liver and testis..
Research Areas
Citations ( 0 )


ELOVL2 could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. This protein may catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative (By similarity).


Illig,T.,, Nat. Genet. 42 (2), 137-141 (2010)
Tanaka,T.,, PLoS Genet. 5 (1), E1000338 (2009)

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$ 325.00
$ 109.00
Cat# AP9191a
Availability: In Stock
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