DPYD Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, FC, ICC |
---|---|
Primary Accession | Q12882 |
Clonality | Monoclonal |
Other Names | DHP; DHPDHase; DPD; DPYD; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 111401 Da |
Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human DPYD |
Description | Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | DPYD (HGNC:3012) |
---|---|
Function | Involved in pyrimidine base degradation (PubMed:1512248). Catalyzes the reduction of uracil and thymine (PubMed:1512248). Also involved the degradation of the chemotherapeutic drug 5-fluorouracil (PubMed:1512248). |
Cellular Location | Cytoplasm. |
Tissue Location | Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells |

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