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>   home   >   Products   >   Primary Antibodies   >   ACTR5 Antibody (C-term)   

ACTR5 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ACTR5 Antibody (C-term) AP9266b
    Western blot analysis of ACTR5 Antibody (C-term) (Cat. #AP9266b) in CHO cell line lysates (35ug/lane). ACTR5 (arrow) was detected using the purified Pab.
  • IHC-P - ACTR5 Antibody (C-term) AP9266b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with ACTR5 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q9H9F9
Reactivity Human, Hamster
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68297 Da
Antigen Region 539-568 aa
Additional Information
Gene ID 79913
Other Names Actin-related protein 5, hARP5, Sarcoma antigen NY-SAR-16, ACTR5, ARP5
Target/Specificity This ACTR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the C-terminal region of human ACTR5.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsACTR5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACTR5
Synonyms ARP5
Function Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.
Cellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling (PubMed:19014934). Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses (PubMed:18163988)
Citations (0)

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Background

ACTR5 may be involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex

References

Kitayama,K., et.al., Exp. Cell Res. 315 (2), 206-217 (2009)
Jin,J., et.al., J. Biol. Chem. 280 (50), 41207-41212 (2005)
Lee,S.Y., et.al., Proc. Natl. Acad. Sci. U.S.A. 100 (5), 2651-2656 (2003)

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$ 325.00
$ 109.00
Cat# AP9266b
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