DPF2 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC, ICC, IP |
|---|---|
| Primary Accession | Q92785 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | BAF45D; DPF2; REQ; UBID4; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 44155 Da |
| Dilution | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human DPF2 |
| Description | May be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. Might also have a role in the development and maturation of lymphoid cells. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | DPF2 |
|---|---|
| Synonyms | BAF45D, REQ, UBID4 |
| Function | Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:27775714, PubMed:28533407). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway (PubMed:20460684). |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Ubiquitous. |

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