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GFPT1 Antibody

Rabbit mAb

     
  •  - GFPT1 Antibody AP92844
    Western blot analysis of GFPT1 expression in MCF7 cell lysate.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IP
Primary Accession Q06210
Reactivity Rat
Clonality Monoclonal
Other Names CMS12; CMSTA1; GFA; GFAT; GFAT1; GFAT1m; GFPT; Gfpt1; GFPT1L; Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Hexosephosphate aminotransferase 1;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 78806 Da
Additional Information
Dilution WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human GFPT1
Description Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name GFPT1
Synonyms GFAT, GFPT
Function Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed:26887390).
Tissue Location Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
Research Areas
Citations (0)
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$ 385.00
$ 195.00
Cat# AP92844
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