PRD Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P12955 |
Clonality | Monoclonal |
Other Names | Pep4; pepD; Peptidase 4; Peptidase D; Prolidase; Proline dipeptidase; X pro dipeptidase; |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 54548 Da |
Dilution | WB 1:500~1:2000 |
---|---|
Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human PRD |
Description | Splits dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position. Plays an important role in collagen metabolism because the high level of iminoacids in collagen. |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | PEPD {ECO:0000303|PubMed:8198124, ECO:0000312|HGNC:HGNC:8840} |
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Function | Dipeptidase that catalyzes the hydrolysis of dipeptides with a prolyl (Xaa-Pro) or hydroxyprolyl residue in the C-terminal position (PubMed:17081196, PubMed:35165443). The preferred dipeptide substrate is Gly-Pro, but other Xaa-Pro dipeptides, such as Ala-Pro, Met-Pro, Phe-Pro, Val-Pro and Leu-Pro, can be cleaved (PubMed:17081196). Plays an important role in collagen metabolism because the high level of iminoacids in collagen (PubMed:2925654). |

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