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TFPT Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TFPT Antibody (N-term) AP9304a
    Western blot analysis of TFPT Antibody (N-term) (Cat. #RB24776) in MDA-MB435 cell line lysates (35ug/lane). TFPT (arrow) was detected using the purified Pab.
    detail
  • FC - TFPT Antibody (N-term) AP9304a
    TFPT Antibody (N-term) (Cat. #AP9304a) flow cytometric analysis of MDA-MB435 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, WB, E
Primary Accession P0C1Z6
Other Accession Q9JMG6, Q3U1J1, Q17QH7
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 28278 Da
Antigen Region 60-88 aa
Additional Information
Gene ID 29844
Other Names TCF3 fusion partner, INO80 complex subunit F, Protein FB1, TFPT, INO80F
Target/Specificity This TFPT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-88 amino acids from the N-terminal region of human TFPT.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTFPT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TFPT
Synonyms INO80F
Function Appears to promote apoptosis in a p53/TP53-independent manner.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

TFPT component of the chromatin-remodeling INO80 complex which, in addition to chromatin remodeling implicated in crucial functions such as DNA repair, checkpoint regulation, DNA replication, telomemere maintenance and chromosome segregation. This protein appears to promote apoptosis in a TP53/p53-independent manner.

References

Jiang,F., et.al., Cancer Lett. 253 (2), 265-272 (2007)
Franchini,C., et.al., Apoptosis 11 (12), 2217-2224 (2006)
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)

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$ 365.00
$ 140.00
Cat# AP9304a
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