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RAB22A Antibody

Rabbit mAb

     
  • WB - RAB22A Antibody AP93155
    Western blot analysis of RAB22A expression in (1) MCF-7 cell lysate; (2) BxPC-3 cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, ICC, IP
Primary Accession Q9UL26
Reactivity Rat
Clonality Monoclonal
Other Names Rab22; RAB22A;
Isotype Rabbit IgG
Host Rabbit
Calculated MW 21855 Da
Additional Information
Dilution WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50
Purification Affinity-chromatography
Immunogen A synthesized peptide derived from human RAB22A
Description Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905).
Storage Condition and Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Protein Information
Name RAB22A
Synonyms RAB22
Function Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).
Cellular Location Endosome membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Cell membrane {ECO:0000250|UniProtKB:P51154}; Lipid-anchor. Early endosome. Late endosome {ECO:0000250|UniProtKB:P51154}. Cell projection, ruffle. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Note=Recruited to phagosomes containing S.aureus or M.tuberculosis.
Research Areas
Citations (0)
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$ 385.00
$ 195.00
Cat# AP93155
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