COQ5 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q5HYK3 |
Other Accession | Q4G064, Q9CXI0, Q0P5A2 |
Reactivity | Human, Mouse |
Predicted | Bovine, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 37140 Da |
Antigen Region | 213-241 aa |
Gene ID | 84274 |
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Other Names | 2-methoxy-6-polyprenyl-1, 4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5, COQ5 |
Target/Specificity | This COQ5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-241 amino acids from the Central region of human COQ5. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | COQ5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | COQ5 {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000312|HGNC:HGNC:28722} |
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Function | Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). |
Cellular Location | Mitochondrion inner membrane {ECO:0000255|HAMAP- Rule:MF_03191, ECO:0000269|PubMed:25152161, ECO:0000269|PubMed:35614220}; Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000269|PubMed:25152161}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03191, ECO:0000269|PubMed:25152161} |
Tissue Location | Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
References
Suzuki,Y., et.al., Genome Res. 14 (9), 1711-1718 (2004)
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