Collagen II Antibody
Rabbit pAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, ICC |
---|---|
Primary Accession | P02458 |
Reactivity | Rat |
Clonality | Polyclonal |
Other Names | Alpha-1 type II collagen; ANFH; AOM; cartilage collagen; Chondrocalcin; CO2A1; COL11A3; COL2A1; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1; MGC131516; SEDC |
Isotype | Rabbit IgG |
Host | Rabbit |
Calculated MW | 141785 Da |
Dilution | WB 1:500~1:2000 |
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Purification | Affinity-chromatography |
Immunogen | A synthesized peptide derived from human Collagen II |
Description | COL2A1 Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Belongs to the fibrillar collagen family. Homotrimers of alpha 1(II) chains. 3 isoforms of the human protein are produced by alternative splicing |
Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
Name | COL2A1 (HGNC:2200) |
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Function | Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793} |
Tissue Location | Isoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte. |

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