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DCA15 Rabbit Polyclonal Antibody
DCA15 Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q66K64 |
| Reactivity | Human, Mouse |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 66463 Da |
| Gene ID | 90379 |
|---|---|
| Other Names | DDB1- and CUL4-associated factor 15, DCAF15 {ECO:0000303|PubMed:28437394, ECO:0000312|HGNC:HGNC:25095} |
| Dilution | WB~~1:1000 |
| Storage Conditions | -20℃ |
| Name | DCAF15 {ECO:0000303|PubMed:28437394, ECO:0000312|HGNC:HGNC:25095} |
|---|---|
| Function | Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins (PubMed:16949367, PubMed:31452512). The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3 (PubMed:31452512). May play a role in the activation of antigen- presenting cells (APC) and their interaction with NK cells (PubMed:31452512). |
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP93462
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