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GALR1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | P47211 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38953 Da |
| Antigen Region | 174-200 aa |
| Gene ID | 2587 |
|---|---|
| Other Names | Galanin receptor type 1, GAL1-R, GALR-1, GALR1, GALNR, GALNR1 |
| Target/Specificity | This GALR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the Central region of human GALR1. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GALR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GALR1 |
|---|---|
| Synonyms | GALNR, GALNR1 |
| Function | Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GALR1 elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart.
References
Borroto-Escuela,D.O. Biochem. Biophys. Res. Commun. 393 (4), 767-772 (2010)
Gratacos,M. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816
Marroni,F. Circ Cardiovasc Genet 2 (4), 322-328 (2009)
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