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SG1D1 Rabbit Polyclonal Antibody
SG1D1 Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, IF |
|---|---|
| Primary Accession | O95968 |
| Reactivity | Rat, Human |
| Host | Polyclonal, Rabbit,IgG |
| Clonality | Polyclonal |
| Calculated MW | 9898 Da |
| Gene ID | 10648 |
|---|---|
| Other Names | Secretoglobin family 1D member 1, Lipophilin-A, SCGB1D1, LIPHA, LPNA |
| Dilution | IHC~~1:100~500 IF~~1:50~200 |
| Storage Conditions | -20℃ |
| Name | SCGB1D1 |
|---|---|
| Synonyms | LIPHA, LPNA |
| Function | May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones. |
| Cellular Location | Secreted. |
| Tissue Location | Expressed in lachrymal gland, thymus, kidney, testis, ovary and salivary gland |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008],
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