HCCA2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | Q70IA6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26927 Da |
| Antigen Region | 5-32 aa |
| Gene ID | 81532 |
|---|---|
| Other Names | MOB kinase activator 2, HCCA2, Mob2 homolog, Mps one binder kinase activator-like 2, MOB2, HCCA2 |
| Target/Specificity | This HCCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-32 amino acids from the N-terminal region of human HCCA2. |
| Dilution | WB~~1:1000 FC~~1:10~50 IHC-P~~1:50~100 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HCCA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MOB2 |
|---|---|
| Synonyms | HCCA2 |
| Function | Stimulates the autophosphorylation and kinase activity of STK38 and STK38L. |
| Cellular Location | Nucleus. Cytoplasm, perinuclear region |

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Provided below are standard protocols that you may find useful for product applications.
Background
HCCA2 binds to and stimulates the kinase activity of the related human serine-threonine kinases NDR1 and NDR2.
References
Devroe,E. J. Biol. Chem. 279 (23), 24444-24451 (2004)
Doyu,M. Brain Res. Mol. Brain Res. 87 (1), 1-11 (2001)
Venter,J.C. Science 291 (5507), 1304-1351 (2001)
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