Trk (pan) (17J17) Rabbit Monoclonal Antibody
Trk (pan) (17J17) Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IP |
---|---|
Primary Accession | P04629, Q16620, Q16288 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Dilution | WB~~1:1000 IP~~N/A |
---|---|
Storage Conditions | -20℃ |

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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]

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